The Analysis of Incidence of Selected Types of Bird Defects in the Czech Republic according to a Multiplicity of Pregnancy
Authors:
V. Gregor 1,2; A. Šípek 1,3; J. Horáček 1; A. Šípek jr. 4; P. Langhammer 5
Authors‘ workplace:
Oddělení lékařské genetiky, Fakultní Thomayerova nemocnice, Praha, ředitel MUDr. K. Filip, CSc., MBA
1; Institut postgraduálního vzdělávání ve zdravotnictví, Praha, Katedra lékařské genetiky, ředitel MUDr. Z. Hadra
2; Ústav pro péči o matku a dítě, Praha-Podolí, ředitel doc. MUDr. J. Feyereisl, CSc.
3; 1. lékařská fakulta Univerzity Karlovy, děkan prof. MUDr. T. Zima, DrSc., MBA
4; Ústav zdravotnických informací a statistiky České republiky, ředitelka Mgr. V. Mazánková
5
Published in:
Ceska Gynekol 2008; 73(4): 199-208
Overview
Objective:
To analyze an occurrence of selected types of birth defects in single and multiple pregnancies in the Czech Republic in 1994–2006 period.
Design:
A retrospective epidemiological analysis of birth defects according to a multiplicity of pregnancy.
Setting:
Department of Medical Genetics, Thomayer’s University Hospital, Prague.
Chair of Medical Genetics, Postgraduate Medical Institute, Prague.
Methods:
Data were collected from National Birth Defects Register (Institute of Health Information and Statistics). Incidences of selected types of birth defects according to pregnancy multiplicity were analyzed.
Results:
In 1994–2006, totally 1 132 567 children were born in the Czech Republic, out of which more than 42 000 with a birth defect. In all particular defects, incidences were increased in children born from multiple pregnancies compared to singletons.
Conclusion:
Highest differences in birth defects incidences in children born from single versus multiple pregnancies were found in neural tube defects group and in congenital hydrocephalus.
Key words:
birth defect, incidence, twins, anencephaly, spina bifida, encephalocele, neural tube defects, congenital hydrocephalus, omfalocele, gastroschisis, abdominal wall defects, oesophageal defects, anorectal malformations, diaphragmatic hernia, renal agenesis/hypoplasia, cystic kidney, Down syndrome, Czech Republic.
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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2008 Issue 4
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