Condylomata acuminata (genital warts)

Czech version

Authors: F. Rob; Z. Kružicová; D. Vaňousová; J. Hercogová
Authors‘ workplace: Centrum pro HPV, Dermatovenerologická klinika 2. LF UK, FN Motol a Nemocnice Na Bulovce, Praha, přednostka prof. MUDr. J. Hercogová
Published in: Ceska Gynekol 2014; 79(5): 399-406

Overview

Infection with human papillomavirus is the most common viral sexually transmitted infection that mainly affects younger sexually active population. Genital warts are one of the most common manifestations of this infection. Although not a life-threatening disease, it is difficult to treat and frequent recurrence can traumatize the patient and influence not only his sexual life. Currently there are many treatment possibilities, but none is 100% efficient. Because of the wide range of character manifestation and their different localization is necessary to approach each patient individually. Therefore, there is a major weapon against this disease prevention, a safe sexual behavior and a new vaccination.

Keywords:
condylomata acuminata, HPV infection, diagnostics, prevention, treatment

Sources

1. Allen, AL., Siegfried, EC. The natural history of condyloma in children. J Am Acad Dermatol, 1998, 39, p. 951–955.

2. Armbruster-Moraes, E., Ioshimoto, LM., et al. Presence of human papillomavirus DNA in amniotic fluids of pregnant women with cervical lesions. Gynecol Oncol, 1994, 54, p. 152–158.

3. Brown, DR., Schroeder, JM., et al. Detection of multiple human papillomavirus types in condylomata acuminata lesions from otherwise healthy and immunosuppressed patients. J Clin Microbiol, 1999, 37, p. 3316–3322.

4. Chelimo, C., Wouldes, TA., Cameron L., et al. Risk factors for and prevention of human papillomaviruses (HPV), genital warts and cervical cancer. J Infect, 2012, 26, p. 310–316.

5. Culton, DA., Morrell, DS., Burkhart, CN. The management of condyloma acuminata in the pediatric population. Pediatr Ann, 2009, 38, p. 368–372.

6. Dvořáková, K., Hercogová, J., et al. Kožní projevy u HIV-pozitivních pacientů. Čes-slov Derm, 2001, 5, s. 227–236.

7. French, L., Nashelsky, J. Clinical inquiries. What is the most effective treatment for external genital warts? J Farm Pract, 2002, 51(4), p. 313.

8. Garland, SM., Skinner, SR., et al. Adolescent and young adult HPV vaccination in Australia: achievements and challenges. Prev Med, 2011, 53, p. 29–35.

9. Garland, SM., Steben, M., Sings, HL., et al. Natural history of genital warts: analysis of the placebo arm of 2 randomized phase III trials of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine. J Infect Dis, 2009, 199, p. 805–814.

10. Gormley, RH., Kovarik, CL. Human papillomavirus-related genital disease in the immunocompromised host: Part I. J Am Acad Dermatol, 2012, 66, p. 86.

11. Hamouda, T., Freij, MA., Saleh, M. Management of genital warts in pregnancy. Clin Exp Obstet Gynecol, 2012, 39, p. 242–244.

12. Hercogová, J. Codylomata acuminata. Farmakoterapie, 2006, 2, s. 1.

13. Hernandez, BY., Wilkens, LR., et al. Transmission of human papillomavirus in heterosexual couples. Emerg Infect Dis., 2008, 14, p. 888–894.

14. Jones, V., Smith, SJ., Omar, HA. Nonsexual transmission of anogenital warts in children: a retrospective analysis. Sci World J, 2007, 7, p. 1896–1899.

15. Koutsky, L. Epidemiology of genital human papillomavirus infection. Am J Med., 1997, 102, p. 3–8.

16. Mashiah, J., Brenner, S. Possible mechanisms in the induction of vitiligo-like hypopigmentation by topical imiquimod. Clin Exp Dermatol, 2008, 33, p. 74–76.

17. Mortensen, GL., Larsen, HK. The quality of life of patients with genital warts: a qualitative study. BMC Public Health, 2010, 10, p. 113.

18. Morton, CA., et al. Guidelines for topical photodynamic therapy: update. Br J Dermatol, 2008, 159, p. 1245–1266.

19. Rob, F., Kružicová, Z., Vaňousová, D., Hercogová, J. Con-

dylomata acuminata. Čs Dermat, 2012, 4, s. 212–219.

20. Rob, F., Kružicová, Z., Vaňousová, D., Hercogová, J. Prevence a léčba genitálních bradavic. Lék Listy, 2013, 3, s. 17–20.

21. Rozehnalová, Z., Hercogová, J. Současné postavení imiquimodu v dermatologii. Farmakoterapie, 2007, 8, s. 211–214.

22. Scheinfeld, N., Lehman, DS. An evidence-based review of medical and surgical treatments of genital warts. Dermatol Online J., 2006, 12(3), p. 5.

23. Silverberg, MJ., Thorsen, P. Condyloma in pregnancy is strongly predictive of juvenile-onset recurrent respiratory papillomatosis. Obstet Gynecol, 2003, 101, p. 645–652.

24. Sinclair, KA., Woods, CR., et al. Anogenital and respiratory tract human papillomavirus infections among children: age, gender, and potential transmission through sexual abuse. Pediatrics, 2005, 116, s. 815–825.

25. Stockfelth, E., Beti, H., Orasan, R. Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial. Br J Dermatol, 2008, 158(6), p. 1329–1338.

26. Tabrizi, SN., Garland, SM., et al. Fall in human papillomavirus prevalence following a national vaccination program. J Infect Dis, 2012, 206, p. 1645–1651.

27. Tachezy, R., Smahelova, J. Human papillomavirus genotype distribution in Czech women and men with diseases etiologically linked to HPV. PloS One, 2011, 6, Epub 2011, Jul 13.

28. Vaňousová, D., Bernardová, J., Sýkorová, B. Uretritidy z pohledu dermatovenerologa. Postgraduální medicína, 2010, 4, s. 466–472.

29. Worwoski, KA., Berman, SM. Sexually transmitted diseases treatment guidelines 2010. MMWR Recomm Rep., 2010, 59, p. 1–110.