Nine-valent HPV vaccine - new generation of HPV vaccine
Authors:
Tomáš Fait 1,2
; V. Dvořák 1,4; R. Pilka 1,3
Authors‘ workplace:
HPV College o. s., prezident MUDr. J. Ondruš, CSc., MIAC
1; Gynekologicko-porodnická klinika 1. LF UK a VFN, Praha, přednosta prof. MUDr. A. Martan, DrSc.
2; Porodnicko-gynekologická klinika FN a LP UP, Olomouc, přednosta prof. MUDr. R. Pilka, Ph. D.
3; Centrum ambulantní gynekologie a primární péče, Brno
4
Published in:
Ceska Gynekol 2015; 80(6): 397-400
Overview
Objective:
To evaluate current knowledge about new generation of HPV vaccine – nine-valent vaccine Gardasil9.
Design:
Review article.
Results:
The nine-valent vaccine against HPV 6/11/16/18/31/33/45/52/58 could improve efficacy of quadrivalent vaccine from 70 to 90 percent for cervical cancer. In addition this vaccine has covered around85-90% of HPV-related vulvar, vaginal and anal cancers. Efficacy and immunogenicity against HPV 6/11/16/18 is the same as for quadrivalent vaccine. Efficacy against HPV 31/33/45/52/58 associated lesions is 97%.
Keywords:
HPV infection, prevention, nine-valent HPV vaccine
Sources
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Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2015 Issue 6
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