Coeliac disease as a possible cause of some gynecological and obstetric abnormalities
Authors:
K. Fiolková; K. Biringer; M. Hrtánková; R. Fiolka; J. Danko
Authors‘ workplace:
Gynekologicko-pôrodnícka klinika UNM, Jesseniova lekárska fakulta UK, Martin
přednosta prof. MUDr. J. Danko, CSc.
Published in:
Ceska Gynekol 2016; 81(6): 470-476
Overview
Objective:
To bring a review of available literature sources on the prevalence of coeliac disease and its possible impact on gynecological and obstetric disorders.
Design:
Review article.
Setting:
Gynecology and Obstetrics Clinic, Jessenius Faculty of Medicine, Comenius University in Bratislava, Martin, Slovakia.
Methods:
Analysis of literary sources.
Conclusion:
Coeliac disease is an autoimmune enteropathy caused by abnormal immune system response to gluten. Over the last decade when the prevalence of the disease increases rapidly confirming the relationship between coeliac disease and a range of reproductive disorders. Problems in this area are mostly confirmed in untreated women. Among the atypical symptoms of coeliac disease also include infertility such as delayed onset of menstruation, early menopause, secondary amenorrhea, infertility and pregnancy complications, such as recurrent abortions, intrauterine fetal growth restriction, small fetus for gestational age, low birth weight and premature birth.
Keywords:
coeliac disease, infertility, pregnancy complications
Sources
1. Anjum, N., Baker, PN., Robinson, NJ., Aplin, JD. Maternal celiac disease autoantibodies bind directly to syncytiotrophoblast and inhibit placental tissue transglutaminase activity. Reprod Biol Endocrinol, 2009, 19, p. 7–16.
2. Bedwal, RS., Bahuguna, A. Zinc, copper and selenium in reproduction. Experientia, 1994, 50, p. 626–640.
3. Bingley, PJ., Williams, AJ., Norcross, AJ., et al. Avon Longitudinal Study of Parents and Children Study Team. Undiagnosed coeliac disease at age seven: population based prospective birth cohort study. BMJ, 2004, 328, p. 322–323.
4. Caputo, I., Barone, MV., Lepretti, M., et al. Celiac anti-tissue transglutaminase antibodies interfere with the uptake of alpha gliadin peptide 31–43 but not of peptide 57–68 by epithelial cells. Biochim Biophys Acta, 2010, 1802, p. 717–727.
5. Cervio, E., Volta, U., Verri, M., et al. Sera of patients with celiac disease and neurologic disorders evoke a mitochondrial-dependent apoptosis in vitro. Gastroenterology, 2007, 133, p. 195–206.
6. Ciacci, C., Cirillo, M., Auriemma, G., et al. Celiac disease and pregnancy outcome. Am J Gastroenterol, 1996, 91, p. 718–722.
7. Collin, P., Vilska, S., Heinonen, PK., et al. Infertility and coeliac disease. Gut, 1996, 39, p. 382–384.
8. Di Simone, N., Silano, M., Castellani, R., et al. Anti-tissue transglutaminase antibodies from celiac patients are responsible for trophoblast damage via apoptosis in vitro. Am J Gastroenterol, 2010, 105, p. 2254–2261.
9. Di Simone, N., De Spirito, M., Di Nicuolo, F., et al. Potential new mechanisms of placental damage in celiac disease: anti-transglutaminase antibodies impair human endometrial angiogenesis. Biol Reprod, 2013, 89, p. 88.
10. Dickey, W., Stewart, F.. Nelson, J., et al. Screening for coeliac disease as a possible maternal risk factor for neural tube defect. Clin Genet, 1996, 49, p. 107–108.
11. Dieterich, W., Ehnis, T., Bauer, M., et al. Identification of tissue transglutaminase as the utoantigen of celiac disease. Nature Med, 1997, 3, p. 797–801.
12. Eliakim, R., Sherer, DM. Celiac disease: fertility and pregnancy. Gynecol Obstet Invest, 2001, 51, p. 3–7.
13. Fasano, A., Berti, I., Gerarduzzi, T., et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med, 2003, 163, p. 286–292.
14. Fasano, A., Catassi, C. Clinical practice. Celiac disease. N Engl J Med, 2012, 20, p. 2419–2426.
15. Ferguson, R., Holmes, GK., Cooke, WT. Coeliac disease, fertility, and pregnancy. Scand J Gastroenterol, 1982, 17, p. 65–68.
16. Guandalini, S., Assiri, A. Celiac disease: a review. JAMA Pediatr, 2014, 168, p. 272–285.
17. Haapalahti, M., Kulmala, P., Karttunen, TJ., et al. Nutritional status in adolescents and young adults with screen-detected celiac disease. J Pediatr Gastroenterol Nutr, 2005, 40, p. 566–570.
18. Hadziselimovic, F., Geneto, R., Buser, M. Celiac disease, pregnancy, small for gestational age: role of extravillous trophoblast. Fetal Pediatr Pathol, 2007, 26, p. 125–134.
19. Helige, C., Ahammer, H., Hammer, A., et al. Trophoblastic invasion in vitro and in vivo: similarities and differences. Hum Reprod, 2008, 23, p. 2282–2291.
20. Hogberg, L., Danielsson, L., Jarleman, S., et al. Serum zinc in small children with coeliac disease. Acta Paediatr, 2009, 98, p. 343–345.
21. Husby, S., Koletzko, S., Korponay-Szabó, IR., et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr., 2012, 54, p. 136–160.
22. Chichili, GR., Rodgers, W. Cytoskeleton-membrane interactions in membrane raftstructure. Cell Mol Life Sci, 2009, 66, p. 2319–2328.
23. Choi, JM., Lebwohl, B., Wang, J., et al. Increased prevalence of celiac disease in patients with unexplained infertility in the United States. J Reprod Med, 2011, 56, p. 199–203.
24. Jabri, B., Sollid, LM. Mechanisms of disease: immunopathogenesis of celiac disease. Nat Clin Pract Gastroenterol Hepatol, 2006, 3, p. 516–525.
25. Jameson, S. Zinc deficiency in malabsorption states: a cause of infertility? Acta Med Scand, 1976, Wiley Online Library.
26. Khurana, S. Role of actin cytoskeleton in regulation of ion transport: examples from epithelial cells. J Membr Biol, 2000, 178, p. 73–87.
27. Kotze, LM. Gynecologic and obstetric findings related to nutritional status and adherence to a gluten-free diet in Brazilian patients with celiac disease. J Clin Gastroenterol, 2004, 38, p. 567–574.
28. Kumar, A., Meena, M., Begum, N., et al. Latent celiac disease in reproductive performance of women. Fertil Steril, 2011, 95, p. 922–927.
29. Ludvigsson, JF., Montgomery, SM., Ekbom A. Celiac disease and risk of adverse fetal outcome: a population-based cohort study. Gastroenterology, 2005, 129, p. 454–463.
30. Maki, M., Lohi, O. Enteropathy. In: Walker, WA., Goulet, O., Kleinman, R., Sherman, P., Sheinder, B., Sanderson, I. (eds). Pediatric gastrointestinal disease. Hamilton, ONT, Canada: BC Decker Inc., 2004, p. 932–943.
31. Maki, M., Mustalahti, K., Kokkonen, J., et al. Prevalence of celiac disease among children in Finland. N Engl J Med, 2003, 348, p. 2517–2524.
32. Machado, AP., Silva, LR., Zausner, B., et al. Undiagnosed celiac disease in women with infertility. J Reprod Med, 2013, 58, p. 61–66.
33. Martinelli, P., Troncone, R., Paparo, F., et al. Coeliac disease and unfavourable outcome o pregnancy. Gut, 2000, 46, p. 332–335.
34. Meloni, GF., Dessole, S., Vargiu, N., et al. The prevalence of coeliac disease in infertility. Hum Reprod, 1999, 14, p. 2759–2761.
35. Minas, V., Jeschke, U., Kalantaridou, SN., et al. Abortion is associated with increased expression of FasL in decidual leukocytes and apoptosis of extravillous trophoblasts: a role for CRH and urocortin. Mol Hum Reprod, 2007, 13, p. 663–673.
36. Morris, JS., Adjukiewicz, AB., Read, AE. Coeliac infertility: an indication for dietary gluten restriction. Lancet, 1970, 1, p. 213.
37. Murray, JA., Van Dyke, C., Plevak, MF., et al. Trends in the identification and clinical features of celiac disease in a North American community, 1950–2001. Clin Gastroenterol Hepatol, 2003, p. 19–27.
38. Murray, MJ., Lessey, BA. Embryo implantation and tumor metastasis: common pathways of invasion and angiogenesis. Semin Reprod Endocrinol, 1999, 17, p. 275–290.
39. Nenna, R., Mennini, M., Petrarca, L., et al. Immediate effect on fertility of a gluten-free diet in women with untreated coeliac disease. Gut, 2011, 60, p. 1023–1024.
40. Park, D., Choi, SS., Ha, KS. Transglutaminase 2: a multifunctional protein in multiple subcellular compartments. Amino Acids, 2010, 39, p. 619–631.
41. Riddle, MS., Murray, JA., Porter, CK. The incidence and risk of celiac disease in a healthy US adult population. Am J Gastroenterol., 2012, 107, p. 1248–1255.
42. Robinson, NJ., Glazier, JD., Greenwood, SL., et al. Tissue transglutaminase expression and activity in placenta. Placenta, 2006, 27, p. 148–157.
43. Rostom, A., Dube, C., Cranney, A., et al. The diagnostic accuracy of serologic tests for celiac disease: a systematic review. Gastroenterology, 2005, 128, p. 38–46.
44. Salvati, VM., Mazzarella, G., Gianfrani, C., et al. Recombinant human IL-10 suppresses gliadin-dependent T-cell activation in ex vivo cultured coeliac intestinal mucosa. Gut, 2005, 54, p. 46–53.
45. Santonicola, A., Iovino, P., Cappello, C., et al. Frommenarche to menopause: the fertile life span of celiac women. Menopause, 2011, 18, p. 1125–1130.
46. Sferlazzas, C., Arrigo, T., Salzano, G., et al. Menarcheal age in celiac disease may not be delayed and maybe irrespective of age at diagnosis and dietary management. J Endocrinol Invest, 2008, 31, p. 432–435.
47. Shamaly, H., Mahameed, A., Sharony, A., Shamir, R. Infertility and celiac disease: doweneed more than one serological marker? Acta Obstet Gynecol Scand, 2004, 83, p. 1184–1188.
48. Singhal, N., Alam, S., Sherwani, R., Musarrat, J. Serum zinc levels in celiac disease. Indian Pediatr, 2008, 45, p. 319–321.
49. Smecuol, E., Maurino, E., Vazquez, H., et al. Gynaecological and obstetric disorders in coeliac disease: frequent clinical onset during pregnancy or the puerperium. Eur J Gastroenterol Hepatol, 1996, 8, p. 63–89.
50. Sollid, LM. Coeliac disease: dissecting a complex inflammatory disorder. Nat Rev Immunol, 2002, 2, p. 647–655.
51. Tack, GJ., Verbeek, WHM., Schreurs, MWJ., Mulder, CJJ. The spectrum of celiac disease: epidemiology, clinical aspects and treatment. Nat Rev Gastroenterol Hepatol, 2010, 7, p. 204–213.
52. Tatar, G., Elsurer, R., Simsek, H., et al. Screening of tissue transglutaminase antibody in healthy blood donors for celiac disease screening in the Turkish population. Dig Dis Sci, 2004, 49, p. 1479–1484.
53. Taylor, CM., McLaughlin, B., Weiss, JB., Maroudas, NG. Concentrations o endothelial-cell-stimulating angiogenesis factor, a major component of human uterine angiogenesis factor, in human and bovine embryonic tissues and decidua. J Reprod Fertil, 1992, 94, p. 44544–44549.
54. West, J., Logan, RF., Hill, PG., et al. Seroprevalence, correlates, and characteristics of undetected coeliac disease in England. Gut, 2003, 52, p. 960–965.
55. Wilson, C., Eade, OE., Elstein, M., Wright, R. Subclinical celiac disease and infertility. Brit Med J, 1976, 2, p. 215–216.
56. Yuce, A., Demir, H., Temizel, IN., Kocak, N. Serum carnitine and selenium levels in children with celiac disease. Indian J Gastroenterol, 2004, 23, p. 87–88.
57. Zemskov, EA., Janiak, A., Hang, J., et al. The role of tissue transglutaminase in cell-matrix interactions. Front Biosci, 2006, 1, p. 1057–1076.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2016 Issue 6
Most read in this issue
- Original Bishop score with modifications
- Breast self-examination. Yes or no?
- Cesarean scar ectopic pregnancy
- Cesarean section incidence and vaginal birth success rate at term pregnancy after myomectomy