News and perspectives in uterine fibroids radiotherapy
Authors:
K. Kubínová 1; M. Mára 1; P. Horák 1; R. Kříž. 2; J. Mašková 3; D. Kužel 1
Authors‘ workplace:
Gynekologicko-porodnická klinika VFN a 1. LF UK, Praha, přednosta prof. MUDr. A. Martan, DrSc.
1; Radiodiagnostické oddělení, Nemocnice Na Homolce, Praha, primář doc. MUDr. J. Vymazal, DrSc.
2; Department of Radiology, Royal Infirmary Hospital, Aberdeen, Skotsko
3
Published in:
Ceska Gynekol 2009; 74(1): 22-26
Overview
Uterine artery embolization (UAE) represents radiological treatment of uterine fibroids. It is highly effective and safe mainly in premenopausal patients with symptomatic fibroids and represents an alternative to hysterectomy in a group of women not suitable for minimally invasive surgical treatment (LAVH) and women desiring uterus sparing therapy. The future of UAE lies in optimal selection of patients based on volume-shrinkage prediction and fertility outcome. The second group is represented by methods based on direct fibroid tissue destruction using specific energy under MRI or UZ guidance. The common aim of these two groups is the volume shrinkage as well as the symptomatic relief. The second group is represented by radiofrequency ablation, focused ultrasound surgery, interstitial laser ablation and cryotherapy. Based on their non-surgical, percutaneous approach these can be classified as minimally-invasive methods. The second group of methods is suitable only for patients with the absence of any desire for child bearing due to the absence of their long-term outcome data.
Key words:
uterine fibroids, radiofrequency ablation, focused ultrasound surgery, interstitial laser ablation, cryotherapy.
Sources
1. Bergamini, V., Ghezzi, F., Cromi, A., et al. Laparoscopic radiofrequency thermal ablation: a new approach to symptomatic uterine myomas. Am J Obstet Gynecol, 2005, 192, 3, p. 768-773.
2. Betjes, HE., Stewart, EA. Embolizace myomu pomocí operačního ultrazvuku s vysokou ohniskovou intenzitou. Gynek po promoci, 2007, 7, p. 28-31.
3. Bradley, EA., Reidy, JF., Forman, RG. et. al. Transcatheter uterine artery embolization to treat large uterine fibroids. Br J Obstet Gynaecol, 1998, 105, p. 235-240.
4. Buscarini, L., Rossi, S. Technology for Radiofrequency. Thermal Ablation of Liver Tumors. Semin Laparosc Surg, 1997, 4, p. 96-101.
5. Carpenter, TT., Walker, WJ. Pregnancy following uterine artery embolisation for symptomatic fibroids: a series of 26 completed pregnancies. BJOG, 2005, 112, p. 321-325.
6. Ciavattini, A., Tsiroglou, D., Litta, P., et al. Pregnancy outcome after laparoscopic cryomyolysis of uterine myomas: report of nine cases. J Minim Invasive Gynecol, 2006, 13, p. 141-144.
7. Cowan, BD., Sesekl, PE., Howard, JC., et al. Interventional magnetic resonance imaging cryotherapy of sterine fibroid tumors: preliminary observation. Am J Obstet Gynecol, 2002, 186, 6, p. 1183-1187.
8. Dohi, M., Harada, J., Mogami, T., et al. MR-guided transvaginal cryotherapy of sterine fibroids with horizontál open MRI system: initial experience. Radiat Med, 2004, 22, 6, p. 391-397.
9. Fučíková, Z., Mára, M., Mašková, J., et al. Embolizace děložních tepen při léčbě myomů z pohledu pacientek. Čes Gynek, 2005, 70, s. 383-388.
10. Goldberg, J., Pereira, L., Berghella, V., et al. Pregnancy outcomes after treatment for fibromyomata: uterine artery embolization versus laparoscopic myomectomy. Am J Obstet Gynecol, 2004, 191, p. 18-21.
11. Goodwin, SC., Bradley, LD., Lipman, JC., et al. UAE versus Myomectomy Study Group.Uterine artery embolization versus myomectomy: a multicenter comparative study. Fertil Steril, 2006, 85, p. 14-21.
12. Hald, K., Klow, NE., Qvigstad, E., Istre, O. Laparoscopic occlusion compared with embolization of uterine vessels: a randomized controlled trial. Obstet Gynecol, 2007, 109, p. 20-27.
13. Harman, M., Zeteroglu, S., Arslan, H., et al. Predictive value of magnetic resonance imaging signal and contrast-enhancement characteristics on post-embolization volume reduction of uterine fibroids. Acta Radiol, 2006, 47, p. 427-435.
14. Harth, Y., Hirshowitz, B., Kaplan, B. Modified topical photodynamic therapy of superficial skin tumors, utilizing aminolevulinic acid, penetration enhancers, red light, and hyperthermia. Dermatol Surg, 1998, 24, p. 723-726.
15. Hehenkamp, WJ., Volkers, NA., Donderwinkel, PF., et al. Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids (EMMY trial): peri- and postprocedural results from a randomized controlled trial. Am J Obstet Gynecol, 2005, 193, p. 1618-1629.
16. Hindley, JT., Law, PA., Jockey, M., et al. Clinical outcomes following percutaneous magnetic resonance image guided laser ablation of symptomatic sterine fibroids. Hum Reprod, 2002, 17, 10, p. 2737-2741.
17. Holub, Z. Minimálně invazivní léčba myomu u symptomatických žen pomocí laparoskopicky asistovaného přerušení děložních cév. Závěrečná zpráva Grantu IGA MZd NR 7982-3/2004, 2006.
18. Holub, Z., Mára, M., Kužel, D., et al. Pregnancy outcomes following uterine artery occlusion: prospective multicentric study. Fertil Steril, 2008, 90, 5, p. 1886–1891.
19. Jain, TP., Srivastava, DN., Sahu, RP., et al. Uterine artery embolization for symptomatic fibroids with imaging follow up. Australas Radiol, 2007, 51, p. 246-252.
20. Kim, HS., Tsai, J., Jacobs, MA., Kamel, IR. Percutaneous image-guided radiofrequency thermal ablation for large symptomatic uterine leiomyomata after uterine artery embolization: a feasibility and safety study. J Vasc Interv Radiol, 2007, 18, p. 41-48.
21. Košťál, M., Tošner, J., Náteková, J., Rousková, L. Těhotenství po embolizaci uterinních arterií pro děložní myom. Čes Gyne, 2004, 69, s. 48-50.
22. Kunde, D., Khalaf, Y. Alternatives to hysterectomy for treatment of uterine fibroids. Obstet Gynaecol, 2004, 6, p. 215-221.
23. Law, P., Regan, L. Interstitial thermo-ablation under MRI guidance for the treatment of fibroids. Curr Opin Obstet Gynecol, 2000, 12, p. 277-282.
24. Mára, M., Mašková, J., Fučíková, Z., et al. Praktické poznámky k embolizaci děložních myomů. Čes Gynek, 2007, 72, s. 58-64.
25. Mára, M., Mašková, J., Fučíková, Z., et al. Midterm clinical and first reproductive results of a randomized controlled trial comparing uterine fibroid embolization and myomectomy. Cardiovasc Intervent Radiol, 2008, 31, p. 73-85.
26. McLucas, B., Goodwin, S., Adler, L., et al. Pregnancy following uterine fibroid embolization. Int J Gynaecol Obstet, 2001, 74, p. 1-7.
27. Moghissi, K., Dixon, K., Thrope, JA., et al. Photodynamic therapy (PDT) in early central lung cancer: a treatment option for patiens inelegible for surgical resection. Torax, 2007, 62, 5, p. 374-375.
28. Nazir, B., Chaturvedi, AK., Rao, A. Image guided radiofrequency ablation of tumors: Current status. Indian J Radiol Imaging, 2003, 13, p. 315-322.
29. Pisco, JM., Bilhim, T., Duarte, M., et al. Pelvic Pain after Uterine Artery Embolization: A Prospective Randomized Study of Polyvinyl Alcohol Particles Mixed with Ketoprofen versus Bland Polyvinyl Alcohol Particles. J Vasc Interv Radiol, 2008, v tisku.
30. Poppe, W., Van Assche, FA., Wilms, G., et al. Pregnancy after transcatheter embolization of a uterine arteriovenous malformation. Am J Obstet Gynecol, 1987, 156, p. 1179-1180.
31. Pron, G., Bennett, J., Common, A., et al. Technical results and effects of operator experience on uterine artery embolization for fibroids: the Ontario uterine fibroid embolization trial. J Vasc Interv Radiol, 2003, 14, p. 545-554.
32. Pron, G., Mocarski, E., Bennett, J., et al. Pregnancy after uterine artery embolization for leiomyomata: the Ontario multicenter trial. Obstet Gynecol, 2005, 105, p. 67-76.
33. Ravina, JH, Herbreteau, D., Ciraru-Vigneron, N., et al. Arterial embolization to treat uterine myomata. Lancet, 1995, 346, p. 671-672.
34. Ravina, JH., Vigneron, NC., Aymard, A., et al. Pregnancy after embolization of uterine myoma: report of 12 cases. Fertil Steril, 2000, 73, p. 1241-123.
35. Razavi, MK., Wolanske, KA., Hwang, GL., et al. Angiographic classification of ovarian artery to uterine artery anastomoses: initial observations in uterine fibroid embolization. Radiology, 2002, 224, p. 707-712.
36. Recaldini, C., Carrafielo, G., Lagana, D., et al. Percutaneous sonographically guided radiofrequency ablation of medium-sized fibroids: feasibility study. Am J Roentgenol, 189, 2007, p. 1303-1306.
37. Sakura, Y., Shimizu, T., Kodama, Y., et al. Magnetic resonance-guidede percutal cryoablation of sterine fibroids: early clinical experience. Cardiovasc Intervent Radiol, 2006, 29, 4, p. 522-528.
38. Spies, JB., Ascher, SA., Roth, AR., et al. Uterine artery embolization for leiomyomata. Obstet Gynecol, 2001, 98, p. 29-34.
39. Stewart, EA., Gostout, B., Rabinovici, J., et al. Sustained relief of leiomyoma symptoms by using focused ultrasound surgery. Obstet Gynecol, 2007, 110, p. 279-287.
40. Volkers, NA., Hehenkamp, WJ., Birnie, E., et al. Uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids: 2 years‘ outcome from the randomized EMMY trial. Am J Obstet Gynecol, 2007, 196, 519, p. e1-e11.
41. Volkers, NA., Hehenkamp, WJ., Smit, P., et al. Economic evaluation of uterine artery embolization versus hysterectomy in the treatment of symptomatic uterine fibroids: results from the randomized EMMY trial. J Vasc Interv Radiol, 2008, 19, p. 1007-1016.
42. Walker, WJ., Pelage, JP. Uterine artery embolisation for symptomatic fibroids: clinical results in 400 women with imaging follow up. Br J Obstet Gynaecol, 2002, 109, p. 1262-1272.
43. Worthington-Kirsch, RL., Popky, GL., Hutchins, FL Jr. Uterine arterial embolization for the management of leiomyomas: quality-of-life assessment and clinical response. Radiology, 1998, 208, p. 625-629.
44. Wu, O., Briggs, A., Dutton, S., et al. Uterine artery embolisation or hysterectomy for the treatment of symptomatic uterine fibroids: a cost-utility analysis of the HOPEFUL study. BJOG, 2007, 114, p. 1352-1362.
Labels
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineArticle was published in
Czech Gynaecology
2009 Issue 1
Most read in this issue
- Thyroid gland in the gravidity
- Spontaneous symphysis pubis rupture followed by intraabdominal bleeding during the vaginal delivery
- The diagnostic value of hysterosalpingography in the diagnosis of tubal disease
- News in pathophysiology and management of preterm labour